Abstract

Review Article

Could apple cider vinegar be used for health improvement and weight loss?

Alexander V Sirotkin*

Published: 26 April, 2021 | Volume 5 - Issue 1 | Pages: 014-016

This non-systematic review outlines the current knowledge concerning provenance, chemical composition and properties of apple cider vinegar, its general health effects, as well as the currently available knowledge concerning its action on fat storage, physiological mechanisms of its effects, as well as its safety and recommended dosage for treatment of obesity. 

Read Full Article HTML DOI: 10.29328/journal.niogb.1001016 Cite this Article Read Full Article PDF

Keywords:

Obesity; Adipocyte; Vinegar; Apple; metabolism

References

  1. Aparecida Silveira E, Vaseghi G, de Carvalho Santos AS, Kliemann N, Masoudkabir F, et al. Visceral Obesity and Its Shared Role in Cancer and Cardiovascular Disease: A Scoping Review of the Pathophysiology and Pharmacological Treatments. Int J Mol Sci. 2020; 21: 9042. PubMed: https://pubmed.ncbi.nlm.nih.gov/33261185/
  2. Heyn GS, Corrêa LH, Magalhães KG. The Impact of Adipose Tissue-Derived miRNAs in Metabolic Syndrome, Obesity, and Cancer. Front Endocrinol (Lausanne). 2020; 11: 563816. PubMed: https://pubmed.ncbi.nlm.nih.gov/33123088/
  3. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. PLoS Med. 2009; 6: e1000097. PubMed: https://pubmed.ncbi.nlm.nih.gov/19621072/
  4. Budak NH, Aykin E, Seydim AC, Greene AK, Guzel-Seydim ZB. Functional properties of vinegar. J Food Sci. 2014; 79: R757-764. PubMed: https://pubmed.ncbi.nlm.nih.gov/24811350/
  5. Kondo S, Tayama K, Tsukamoto Y, Ikeda K, Yamori Y. Antihypertensive effects of acetic acid and vinegar on spontaneously hypertensive rats. Biosci Biotechnol Biochem. 2001; 65: 2690-2694. PubMed: https://pubmed.ncbi.nlm.nih.gov/11826965/
  6. Nazıroğlu M, Güler M, Özgül C, Saydam G, Küçükayaz M, et al. Apple cider vinegar modulates serum lipid profile, erythrocyte, kidney, and liver membrane oxidative stress in ovariectomized mice fed high cholesterol. J Membr Biol. 2014; 247: 667-673. PubMed: https://pubmed.ncbi.nlm.nih.gov/24894721/
  7. Suiryanrayna MV, Ramana JV. A review of the effects of dietary organic acids fed to swine. J Anim Sci Biotechnol. 2015; 6: 45. PubMed: https://pubmed.ncbi.nlm.nih.gov/26500769/
  8. Liljeberg H, Björck I. Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar. Eur J Clin Nutr. 1998; 52: 368-371. PubMed: https://pubmed.ncbi.nlm.nih.gov/9630389/
  9. Fushimi T, Sato Y. Effect of acetic acid feeding on the circadian changes in glycogen and metabolites of glucose and lipid in liver and skeletal muscle of rats. Br J Nutr. 2005; 94: 714-719. PubMed: https://pubmed.ncbi.nlm.nih.gov/16277773/
  10. Johnston CS, Buller AJ. Vinegar and peanut products as complementary foods to reduce postprandial glycemia. J Am Diet Assoc. 2005; 105: 1939-1942. PubMed: https://pubmed.ncbi.nlm.nih.gov/16321601/
  11. Sakakibara S, Yamauchi T, Oshima Y, Tsukamoto Y, Kadowaki T. Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. Biochem Biophys Res Commun. 2006; 344: 597-604. PubMed: https://pubmed.ncbi.nlm.nih.gov/16630552/
  12. Petsiou EI, Mitrou PI, Raptis SA, Dimitriadis GD. Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight. Nutr Rev. 2014; 72: 651-661. PubMed: https://pubmed.ncbi.nlm.nih.gov/25168916/
  13. Russell WR, Baka A, Björck I, Delzenne N, Gao D, et al. Impact of Diet Composition on Blood Glucose Regulation. Crit Rev Food Sci Nutr. 2016; 56: 541-590. PubMed: https://pubmed.ncbi.nlm.nih.gov/24219323/
  14. Shishehbor F, Mansoori A, Shirani F. Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials. Diabetes Res Clin Pract. 2017; 127: 1-9. PubMed: https://pubmed.ncbi.nlm.nih.gov/28292654/
  15. Siddiqui FJ, Assam PN, de Souza NN, Sultana R, Dalan R, et al. Diabetes Control: Is Vinegar a Promising Candidate to Help Achieve Targets? J Evid Based Integr Med. 2018; 23: 2156587217753004. PubMed: https://pubmed.ncbi.nlm.nih.gov/29756472/
  16. Launholt TL, Kristiansen CB, Hjorth P. Safety and side effects of apple vinegar intake and its effect on metabolic parameters and body weight: a systematic review. Eur J Nutr. 2020; 59: 2273-2289. PubMed: https://pubmed.ncbi.nlm.nih.gov/32170375/
  17. Yamashita H. Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats. Crit Rev Food Sci Nutr. 2016; 56: S171-175. PubMed: https://pubmed.ncbi.nlm.nih.gov/26176799/
  18. Johnston CS. Strategies for healthy weight loss: from vitamin C to the glycemic response. J Am Coll Nutr. 2005; 24: 158-165. PubMed: https://pubmed.ncbi.nlm.nih.gov/15930480/
  19. Kondo T, Kishi M, Fushimi T, Ugajin S, Kaga T. Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects. Biosci Biotechnol Biochem. 2009; 73: 1837-1543. PubMed: https://pubmed.ncbi.nlm.nih.gov/19661687/
  20. Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat Commun. 2014; 5: 3611. PubMed: https://pubmed.ncbi.nlm.nih.gov/24781306/
  21. Darzi J, Frost GS, Montaser R, Yap J, Robertson MD. Influence of the tolerability of vinegar as an oral source of short-chain fatty acids on appetite control and food intake. Int J Obes (Lond). 2014; 38: 675-681. PubMed: https://pubmed.ncbi.nlm.nih.gov/23979220/
  22. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc. 2005; 105: 1141-1144. PubMed: https://pubmed.ncbi.nlm.nih.gov/15983536/
  23. Gambon DL, Brand HS, Veerman EC. Unhealthy weight loss. Erosion by apple cider vinegar. Ned Tijdschr Tandheelkd. 2012; 119: 589-591. PubMed: https://pubmed.ncbi.nlm.nih.gov/23373303/
  24. Almenara CA, Aimé A, Maïano C. Vinegar and weight loss in women of eighteenth-century France: a lesson from the past. Hist Psychiatry. 2020; 31: 232-236. PubMed: https://pubmed.ncbi.nlm.nih.gov/31755313/
  25. Lhotta K, Höfle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron. 1998; 80: 242-243. PubMed: https://pubmed.ncbi.nlm.nih.gov/9736833/
  26. Zero DT, Lussi A. Erosion--chemical and biological factors of importance to the dental practitioner. Int Dent J. 2005; 55: 285-290. PubMed: https://pubmed.ncbi.nlm.nih.gov/16167607/

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